Natalie Talmadge and Buster Keaton (1921)
When he married Natalie Talmadge, the Talmadge family was one of the great acting dynasties in both theater and film, and the gossip in Hollywood was that Keaton married her to gain respect in the industry, a rumor he never quite lived down during his peak. Ironically, Keaton is the film legend now.
apparently (according to wiki) after the birth of their second son, Talmadge suddenly announced that she no longer wanted sex with Keaton. Although accepting of this exile (imposed on him for reasons he did not understand), Keaton made it clear that he would not go without sex and would find other partners